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Ultra-High-Throughput Clinical Proteomics Reveals Classifiers of COVID-19 Infection

Ultra-High-Throughput Clinical Proteomics Reveals Classifiers of COVID-19 Infection

Messner CB, Demichev V, Wendisch D, Michalick L, White M, Freiwald A, Textoris-Taube K, Vernardis SI, Egger AS, Kreidl M, Ludwig D, Kilian C, Agostini F, Zelezniak A, Thibeault C, Pfeiffer M, Hippenstiel S, Hocke A, von Kalle C, Campbell A, Hayward C, Porteous DJ, Marioni RE, Langenberg C, Lilley KS, Kuebler WM, Mülleder M, Drosten C, Suttorp N, Witzenrath M, Kurth F, Sander LE and Ralser M

The work establishes a rapid clinical-proteomics workflow and applies it to patient samples, revealing host-response patterns and candidate classifiers.

It is a foundational demonstration of scalable clinical proteomics for disease classification.

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