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Performance Characteristics of Zeno Trap Scanning DIA for Sensitive and Quantitative Proteomics at High Throughput

Performance Characteristics of Zeno Trap Scanning DIA for Sensitive and Quantitative Proteomics at High Throughput

Sinn LR, Wang Z, Alvarez CP, Chelur A, Batruch I, Pribil P, Ludwig D, Tate S, Castro-Perez J, Messner CB, Demichev V and Ralser M

The work evaluates Zeno Trap Scanning DIA across quantitative precision, sensitivity, sample input and throughput, defining where the method performs most effectively. It directly advances the fast DIA mass-spectrometry methods that underpin scalable clinical proteomics.

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