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Air pollution exposure in Generation Scotland: molecular fingerprints and health outcomes

Air pollution exposure in Generation Scotland: molecular fingerprints and health outcomes

Robertson JA, Krätschmer I, Richmond A, McCartney DL, Bajzik J, Vernardis S, Corley J, Tomlinson SJ, Vieno M, Chybowska AD, Grauslys A, Smith HM, Brigden C, Messner CB, Zelezniak A, Ralser M, Russ TC, Pearce J, Cox SR, Robinson MR and Marioni RE

The study combines environmental exposure estimates, health-record linkage and multi-omic data from Generation Scotland to identify molecular markers associated with air pollution and smoking.

It demonstrates how population-scale proteomics can reveal exposure-linked biology and support risk stratification in large cohorts.

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