Article

A time-resolved proteomic and prognostic map of COVID-19

A time-resolved proteomic and prognostic map of COVID-19

Demichev V, Tober-Lau P, Lemke O, Nazarenko T, Thibeault C, Whitwell H, Röhl A, Freiwald A, Szyrwiel L, Ludwig D, Correia-Melo C, Aulakh SK, Helbig ET, Stubbemann P, Lippert LJ, Grüning NM, Blyuss O, Vernardis S, White M, Messner CB, et al., Ralser M and Kurth F

world map showing red infection clusters

The study combines dense clinical sampling with quantitative proteomics to follow disease over time and construct prognostic molecular maps.

It establishes the value of repeated, high-throughput blood-proteome measurements for patient stratification and prognosis.

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